The revised EU GMP Annex 11 and FDA 21 CFR Part 11 enforcement are tightening in 2026, is your organisation ready?

2026 enforcement · Annex 11 & 21 CFR Part 11

Audit-ready GxP IT compliance for EU & US regulators.

Get your free compliance assessment

Find out where your systems stand no commitment.

Request Free Assessment →

End-to-end computerized system validation (CSV) aligned with EU GMP Annex 11, FDA 21 CFR Part 11 and GAMP 5, so your next inspection is a confirmation, not a crisis.

100%

500+

AUDIT PASS RATE

SYSTEMS VALIDATED

EU & US specialists — HPRA · EMA · FDA

EudraLex Volume 4 ALCOA+ Qualification (IQ, OQ, PQ) COBIT 2019 ITIL 4 ISO 9001 ISO 31000 ISO 38500 ISO 14971 ICH Q9 (R1) WHO Guidelines (Annex 2) GAMP 5 EU GMP Annex 11 FDA 21 CFR Part 11 ISO 27001

● Why it matters

Close the gaps before inspectors find them.

Missing Annex 11 or Part 11 controls can mean warning letters, halted batches and records that are legally invalid. We build the validated, audit-ready environment that turns every inspection into a formality.

Regulatory certainty

Inspection-ready evidence for EU GMP Annex 11, FDA 21 CFR Part 11 and EudraLex Vol 4 — accepted on both sides of the Atlantic.

ALCOA+ data integrity

Automated, attributable, audit-proof records. Regulators trust your batch and stability data on the first pass.

GAMP 5 validation

IQ / OQ / PQ done right, once. Structured methodology delivers most validations in weeks, not months.

Security & governance

ISO 27001, risk management and GDPR embedded across labs, manufacturing and patient data. Breach risk neutralized.

0%
Audit Pass Rate
0+
Systems Validated
0+
Years Expertise
0+
Enterprise Clients

Trusted by Pharmaceutical, Medtech & Devices, Biotech and regulated Fintech across Europe and the United States.

● INDUSTRIES

Trusted across regulated sectors.

Working with organisations in Ireland's most demanding compliance environments.

● Our method

From planning to production, in 10 validated phases.

A complete GAMP 5 lifecycle. One team owns every phase, every document, every signature, so nothing falls between the cracks at inspection.

1

Planning & Strategy

Validation Master Plan, system Validation Plan and GAP analysis against the regulations.

2

Requirements Specification

User (URS), Functional, Design and Configuration specifications.

3

Risk Assessment

FMEA with RPN scoring and a full requirements traceability matrix (RTM).

4

Test Protocols

IQ / OQ / PQ protocols and reports with objective, audit-ready evidence.

5

Data Integrity & Security

ALCOA+ assessment, audit-trail review, electronic signatures, backup & recovery.

6

IT Governance

BCP/DRP, change, incident, problem and CAPA management, SLAs and OLAs.

7

Information Security (ISO 27001)

Access control (RBAC / SoD), vulnerability, asset and password management.

8

Operation & Support

SOPs, training, system O&M, patch management and periodic review.

9

Suppliers & Third Parties

Supplier assessment, audit and qualification against GAMP 5 and ISO.

10

Final Reports & Approval

Validation Report, deviation closure and formal release to production.

← arraste para ver todas as etapas →

Let's make your next inspection a formality.

One engagement, end-to-end. We build and maintain the entire compliance framework, so you're inspection-ready, always.

© 2026 Quality Engineering. All rights reserved.